Plone 5.1 migration: Shouldn't load state for zope.component.persistentregistry.PersistentAdapterRegistry 0x0861e1 when the connection is closed

Trying to migrate a Plone 4.3 site (some AT, some DX types) to Plone 4.1:

2018-04-19 18:57:47 ERROR ZServerPublisher exception caught
Traceback (most recent call last):
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/Zope2-2.13.27-py2.7.egg/ZServer/PubCore/ZServerPublisher.py", line 31, in __init__
    response=b)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/Zope2-2.13.27-py2.7.egg/ZPublisher/Publish.py", line 455, in publish_module
    environ, debug, request, response)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/Zope2-2.13.27-py2.7.egg/ZPublisher/Publish.py", line 276, in publish_module_standard
    if request is not None: request.close()
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/Zope2-2.13.27-py2.7.egg/ZPublisher/BaseRequest.py", line 220, in close
    notify(EndRequestEvent(None, self))
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/zope.event-3.5.2-py2.7.egg/zope/event/__init__.py", line 31, in notify
    subscriber(event)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/zope.component-4.4.1-py2.7.egg/zope/component/event.py", line 27, in dispatch
    component_subscribers(event, None)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/zope.component-4.4.1-py2.7.egg/zope/component/_api.py", line 139, in subscribers
    return sitemanager.subscribers(objects, interface)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/zope.interface-4.4.3-py2.7-linux-x86_64.egg/zope/interface/registry.py", line 442, in subscribers
    return self.adapters.subscribers(objects, provided)
  File "/home/ajung/sandboxes/ita.buildout-plone5.1/ita.buildout/eggs/ZODB-5.3.0-py2.7.egg/ZODB/Connection.py", line 790, in setstate
    raise ConnectionStateError(msg)
ConnectionStateError: Shouldn't load state for zope.component.persistentregistry.PersistentAdapterRegistry 0x0861e1 when the connection is closed

Unable to access the ZMI..nothing is loading...anyone seen this?

-aj