ImportError: cannot import name md5

My next Problem with PLONE4: my buildout ends with:
"ImportError: cannot import name md5"
Any Hints?

https://python.readthedocs.io/en/v2.7.2/library/md5.html

You use a very old package, locate this package and fix the imports.

Generally: given that you want to clone your production system and attempt a migration: a pragmatic approach may be to find the package versions you need on your production system, pin those in your buildout and copy to your test system.