FWIW, here are comparable results with my branch of plone.dexterity without implicit schema attribute default value lookup: Travis CI - Test and Deploy with Confidence
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Plone 4.3 (plone.app.contenttypes): 0.446 seconds
278378 function calls (259117 primitive calls) in 0.446 seconds
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Plone 5.0: 0.440 seconds
260337 function calls (241383 primitive calls) in 0.440 seconds
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Plone 5.1: 0.493 seconds
308518 function calls (280764 primitive calls) in 0.493 seconds